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Microbes in Human Welfare

Biology · Class 12NCERT pp. 149–1582 sets × 25 questions

Key facts and formulas for Microbes in Human Welfare, three worked sample questions, and two full practice sets. Every question has a hint, a reason for every option and a step-by-step solution, with a calculator or animation where one helps. English and Hinglish.

Key facts for this chapter

IdeaRule or fact
Prion, viroid, virusPrion = protein only; viroid = RNA only; viruses grow only in living host cells
Curd and cheeseLactic acid bacteria make curd, raise vitamin B12; rennet acts on casein; Swiss cheese holes: Propionibacterium (CO2); Roquefort: fungus
Acids by microbesCitric: Aspergillus niger; acetic: Acetobacter aceti; butyric: Clostridium butylicum; lactic: Lactobacillus; ethanol: Saccharomyces
DrinksWine and beer are not distilled; whisky, brandy and rum are distilled
AntibioticsPenicillin: Fleming found it, Chain and Florey proved it; streptomycin from Streptomyces; penicillin blocks cell wall synthesis
Bioactive moleculesStreptokinase: clot buster; cyclosporin A: immunosuppressant; statins: block cholesterol enzyme (Monascus)
Sewage treatmentPrimary: physical; secondary: aeration, flocs, activated sludge; tertiary: nitrates and phosphates; high BOD means more pollution
BiogasMethanogens (archaebacteria) in sludge and rumen; gases: CH4, H2S, CO2; slurry used as fertiliser
BiocontrolLadybird: aphids; dragonfly: mosquitoes; Bt: caterpillars (alkaline gut dissolves crystal); Trichoderma: pathogens; cryIAc: bollworm
BiofertilisersRhizobium: nodules; Azotobacter, Azospirillum: free-living; Anabaena: paddy, Azolla; Glomus: phosphorus; nitrogenase, leghaemoglobin, heterocysts

Three sample questions

Q1. Which of the following infectious agents is made of protein only and has no nucleic acid?
  1. Viroid
  2. Bacteriophage
  3. Adenovirus
  4. Prion
Hint and solution

Hint: The name itself says it: proteinaceous infectious particle.

  1. Prion = proteinaceous infectious particle — The question asks for an agent that has protein but no nucleic acid.
  2. Viruses: nucleic acid + protein coat — Bacteriophage and adenovirus are viruses, so both carry DNA or RNA inside a protein coat.
  3. Viroid: RNA only — A viroid is just a small RNA, so it has nucleic acid and no protein.
  4. Only the prion is protein alone — So the answer is the prion, which is made only of protein. Option D.
Answer: D. Prions are proteinaceous infectious agents.
Q2. Consider the following.
I. Bacteria and many fungi form colonies on a nutrient medium.
II. Viruses form colonies on simple nutrient media.
III. A bacterial colony can be seen without a lens.
Which are correct?
  1. I and III only
  2. I and II only
  3. II and III only
  4. I, II and III
Hint and solution

Hint: Which of these microbes can multiply without a living host cell?

  1. Colony = visible mass from one cell dividing — Bacteria and many fungi divide repeatedly on a nutrient medium and form a visible colony. So I is true.
  2. Viruses multiply only in living host cells — Viruses cannot be grown on simple nutrient media. So II is false.
  3. Colony is seen with the naked eye — A colony is a mass of millions of cells, so no lens is needed. III is true.
  4. I and III are correct — So the answer is the pair of statements I and III. Option A.
Answer: A. Viruses multiply only in living host cells, so II is wrong.
Q3. Match the virus with its host or effect.
Column I: a. Bacteriophage; b. Adenovirus; c. Tobacco Mosaic Virus
Column II: (i) Respiratory infection in humans; (ii) Infects bacteria; (iii) Rod-shaped plant virus
  1. a-(i), b-(ii), c-(iii)
  2. a-(iii), b-(i), c-(ii)
  3. a-(ii), b-(i), c-(iii)
  4. a-(ii), b-(iii), c-(i)
Hint and solution

Hint: Phage means eater of bacteria; TMV has the word tobacco, a plant.

  1. Bacteriophage → infects bacteria — A bacteriophage is a virus whose host is a bacterium. So a matches (ii).
  2. Adenovirus → respiratory infection — Adenovirus causes respiratory infections in humans. So b matches (i).
  3. TMV → rod-shaped plant virus — Tobacco Mosaic Virus infects plants and is rod-like. So c matches (iii).
  4. a-(ii), b-(i), c-(iii) — So the combination is a with ii, b with i, c with iii. Option C.
Answer: C. Bacteriophage infects bacteria; adenovirus causes respiratory infections; TMV is a rod-shaped plant virus.

How to use this chapter

Read the NCERT pages first, then attempt Set 1 without the hints. Note every wrong answer in a mistake list, read the reason for each option, and retry Set 2 two days later. A topic is solid when you can say why each wrong option is wrong.

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