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Chemical Coordination and Integration

Biology · Class 11NCERT pp. 239–2492 sets × 25 questions

Key facts and formulas for Chemical Coordination and Integration, three worked sample questions, and two full practice sets. Every question has a hint, a reason for every option and a step-by-step solution, with a calculator or animation where one helps. English and Hinglish.

Key facts for this chapter

IdeaRule or fact
Hormone definitionNon-nutrient chemical, trace amounts, intercellular messenger; also made by scattered tissues (heart, kidney, gut)
Posterior pituitaryStores and releases oxytocin and ADH made in the hypothalamus
Pars distalis (6)GH, PRL, TSH, ACTH, LH, FSH; MSH is from pars intermedia
Thyroid axisHypothalamus TRH → anterior pituitary TSH → thyroid T3, T4 (negative feedback)
Calcium controlPTH raises blood Ca2+ (bone, kidney, gut); calcitonin from C cells lowers it
DisordersCretinism (child), myxoedema (adult), Graves (hyper), goitre (iodine), acromegaly, Cushing, Addison, DI vs DM
AdrenalCortex from inside: reticularis, fasciculata, glomerulosa; medulla makes adrenaline and noradrenaline
PancreasAlpha cells glucagon (raises glucose); beta cells insulin (lowers glucose); insulin has 21 + 30 = 51 amino acids
Gut and other hormonesGastrin, secretin, CCK, GIP; ANF from heart; erythropoietin from kidney; hCG, relaxin from placenta
Hormone actionPeptides use membrane receptors and second messengers (cAMP); steroids and thyroid hormones use intracellular receptors

Three sample questions

Q1. Consider these statements about hormones.
I. They are non-nutrient chemicals.
II. They are made in trace amounts.
III. They are made only by organised endocrine glands.
IV. They act as intercellular messengers.
Which are correct?
  1. I, II and III only
  2. I, II and IV only
  3. II, III and IV only
  4. I, III and IV only
Hint and solution

Hint: Check whether hormones come only from classic glands, or also from scattered tissues like the gut and heart.

  1. Hormone = non-nutrient, trace, messenger — A hormone is a non-nutrient chemical made in trace amounts that acts as an intercellular messenger. So I, II and IV are true.
  2. III says: only organised glands — Modern endocrinology says hormones are also made by scattered tissues like the heart, kidney and gastrointestinal tract.
  3. III is false — Because of the word only, statement III fails.
  4. Correct set: I, II, IV — The set without III is I, II and IV only. Option B.
Answer: B. Hormones are non-nutrient, trace-amount intercellular messengers. The modern view also includes scattered tissues, so III is wrong.
Q2. Endocrine glands are called ductless because they
  1. have ducts only on one side
  2. release hormones into the gut
  3. do not make any secretion
  4. pour their hormones directly into the blood
Hint and solution

Hint: Ductless means no tube. Think about where the secretion has to go if there is no duct.

  1. Endocrine = ductless — Endocrine glands have no ducts to carry their product.
  2. No duct, so blood is the route — Their hormones are poured directly into the blood or tissue fluid and carried to targets.
  3. Exocrine glands use ducts — Salivary and sweat glands are exocrine and need ducts, so they are not described this way.
  4. Answer — The reason is that they pour hormones directly into the blood. Option D.
Answer: D. They have no ducts; hormones enter the blood directly.
Q3. Assertion (A): The posterior pituitary is a store-house of hormones, not a factory.
Reason (R): Oxytocin and vasopressin are made in the hypothalamus and carried down axons to the posterior pituitary.
  1. Both A and R are true and R is the correct explanation of A
  2. Both A and R are true but R is not the correct explanation of A
  3. A is true but R is false
  4. A is false but R is true
Hint and solution

Hint: Ask where oxytocin and vasopressin are actually made, and then whether R explains why the lobe is only a store.

  1. Oxytocin, ADH made in hypothalamus — The neurosecretory cells of the hypothalamus synthesise both hormones, so R is true.
  2. Axons carry them down — The hormones travel along axons to the posterior pituitary, where they are stored.
  3. A is true — So the posterior pituitary only stores and releases them. It is a store-house, not a factory.
  4. R explains A — Since synthesis happens elsewhere, the lobe has nothing to make, so R explains A. Option A.
Answer: A. The pars nervosa only stores and releases the two hormones made in the hypothalamus, so R explains A.

How to use this chapter

Read the NCERT pages first, then attempt Set 1 without the hints. Note every wrong answer in a mistake list, read the reason for each option, and retry Set 2 two days later. A topic is solid when you can say why each wrong option is wrong.

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